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Mitochondria-targeted antioxidant protects against irradiation-induced salivary gland hypofunction

A severe consequence of radiation therapy in patients with head and neck cancer is persistent salivary gland hypofunction which causes xerostomia and oral infections. We previously showed that irradiation (IR) of salivary glands in mice triggers initial transient increases in mitochondrial reactive...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Liu, Xibao, Subedi, Krishna P., Zheng, Changyu, Ambudkar, Indu
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032724/
https://ncbi.nlm.nih.gov/pubmed/33833270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86927-3
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