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Neurturin Gene Therapy Protects Parasympathetic Function to Prevent Irradiation-Induced Murine Salivary Gland Hypofunction

Head and neck cancer patients treated with irradiation often present irreversible salivary gland hypofunction for which no conventional treatment exists. We recently showed that recombinant neurturin, a neurotrophic factor, improves epithelial regeneration of mouse salivary glands in ex vivo culture...

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Podrobná bibliografie
Vydáno v:Mol Ther Methods Clin Dev
Hlavní autoři: Ferreira, Joao N.A., Zheng, Changyu, Lombaert, Isabelle M.A., Goldsmith, Corinne M., Cotrim, Ana P., Symonds, Jennifer M., Patel, Vaishali N., Hoffman, Matthew P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857485/
https://ncbi.nlm.nih.gov/pubmed/29560384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.02.008
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