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p27 Protein Protects Metabolically Stressed Cardiomyocytes from Apoptosis by Promoting Autophagy

p27(Kip1) (p27), a key regulator of cell division, has been implicated in autophagy of cancer cells. However, its role in autophagy, the evolutionarily conserved catabolic process that enables cells to remove unwanted proteins and damaged organelles, had not been examined in the heart. Here we repor...

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Autors principals: Sun, Xuetao, Momen, Abdul, Wu, Jun, Noyan, Hossein, Li, Renke, von Harsdorf, Rüdiger, Husain, Mansoor
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059136/
https://ncbi.nlm.nih.gov/pubmed/24794871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.542795
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