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Sirt1 promotes autophagy and inhibits apoptosis to protect cardiomyocytes from hypoxic stress
Sirtuin 1 (Sirt1) exerts its cardioprotective effects in various cardiovascular diseases via multiple cellular activities. However, the therapeutic implications of Sirt1 in hypoxic cardiomyocytes and the underlying mechanisms remain elusive. The present study investigated whether Sirt1 regulates aut...
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| Veröffentlicht in: | Int J Mol Med |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6443335/ https://ncbi.nlm.nih.gov/pubmed/30864731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2019.4125 |
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