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Inhibition of cyclin-dependent kinase 2 protects against doxorubicin-induced cardiomyocyte apoptosis and cardiomyopathy

With the rapid increase in cancer survival because of improved diagnosis and therapy in the past decades, cancer treatment–related cardiotoxicity is becoming an urgent healthcare concern. The anthracycline doxorubicin (DOX), one of the most effective chemotherapeutic agents to date, causes cardiomyo...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Xia, Peng, Liu, Yuening, Chen, Jingrui, Coates, Shelby, Liu, David X., Cheng, Zhaokang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314117/
https://ncbi.nlm.nih.gov/pubmed/30361442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004673
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