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Helicase SUV3, Polynucleotide Phosphorylase, and Mitochondrial Polyadenylation Polymerase Form a Transient Complex to Modulate Mitochondrial mRNA Polyadenylated Tail Lengths in Response to Energetic Changes

Mammalian mitochondrial mRNA (mt-mRNA) transcripts are polyadenylated at the 3′ end with different lengths. The SUV3·PNPase complex and mtPAP have been shown to degrade and polyadenylate mt mRNA, respectively. How these two opposite actions are coordinated to modulate mt-mRNA poly(A) lengths is of i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Wang, Dennis Ding-Hwa, Guo, Xuning Emily, Modrek, Aram Sandaldjian, Chen, Chi-Fen, Chen, Phang-Lang, Lee, Wen-Hwa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059117/
https://ncbi.nlm.nih.gov/pubmed/24770417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536540
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