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Human Mitochondrial SUV3 and Polynucleotide Phosphorylase Form a 330-kDa Heteropentamer to Cooperatively Degrade Double-stranded RNA with a 3′-to-5′ Directionality

Efficient turnover of unnecessary and misfolded RNAs is critical for maintaining the integrity and function of the mitochondria. The mitochondrial RNA degradosome of budding yeast (mtEXO) has been recently studied and characterized; yet no RNA degradation machinery has been identified in the mammali...

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Bibliografiske detaljer
Main Authors: Wang, Dennis Ding-Hwa, Shu, Zhanyong, Lieser, Scot A., Chen, Phang-Lang, Lee, Wen-Hwa
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742846/
https://ncbi.nlm.nih.gov/pubmed/19509288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.009605
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