Polynucleotide Phosphorylase Activity May Be Modulated by Metabolites in Escherichia coli

RNA turnover is an essential element of cellular homeostasis and response to environmental change. Whether the ribonucleases that mediate RNA turnover can respond to cellular metabolic status is an unresolved question. Here we present evidence that the Krebs cycle metabolite citrate affects the acti...

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Main Authors: Nurmohamed, Salima, Vincent, Helen A., Titman, Christopher M., Chandran, Vidya, Pears, Michael R., Du, Dijun, Griffin, Julian L., Callaghan, Anastasia J., Luisi, Ben F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077632/
https://ncbi.nlm.nih.gov/pubmed/21324911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200741
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