Polynucleotide Phosphorylase Activity May Be Modulated by Metabolites in Escherichia coli

RNA turnover is an essential element of cellular homeostasis and response to environmental change. Whether the ribonucleases that mediate RNA turnover can respond to cellular metabolic status is an unresolved question. Here we present evidence that the Krebs cycle metabolite citrate affects the acti...

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Bibliographic Details
Main Authors: Nurmohamed, Salima, Vincent, Helen A., Titman, Christopher M., Chandran, Vidya, Pears, Michael R., Du, Dijun, Griffin, Julian L., Callaghan, Anastasia J., Luisi, Ben F.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077632/
https://ncbi.nlm.nih.gov/pubmed/21324911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200741
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