Crystal Structure of Escherichia coli Polynucleotide Phosphorylase Core Bound to RNase E, RNA and Manganese: Implications for Catalytic Mechanism and RNA Degradosome Assembly

Polynucleotide phosphorylase (PNPase) is a processive exoribonuclease that contributes to messenger RNA turnover and quality control of ribosomal RNA precursors in many bacterial species. In Escherichia coli, a proportion of the PNPase is recruited into a multi-enzyme assembly, known as the RNA degr...

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Main Authors: Nurmohamed, Salima, Vaidialingam, Bhamini, Callaghan, Anastasia J., Luisi, Ben F.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723993/
https://ncbi.nlm.nih.gov/pubmed/19327365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.03.051
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