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Crystal structure of Caulobacter crescentus polynucleotide phosphorylase reveals a mechanism of RNA substrate channelling and RNA degradosome assembly

Polynucleotide phosphorylase (PNPase) is an exoribonuclease that cleaves single-stranded RNA substrates with 3′–5′ directionality and processive behaviour. Its ring-like, trimeric architecture creates a central channel where phosphorolytic active sites reside. One face of the ring is decorated with...

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Xehetasun bibliografikoak
Egile Nagusiak: Hardwick, Steven W., Gubbey, Tobias, Hug, Isabelle, Jenal, Urs, Luisi, Ben F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Royal Society 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376730/
https://ncbi.nlm.nih.gov/pubmed/22724061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.120028
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