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Age-related Marrow Adipogenesis Is Linked to Increased Expression of RANKL

With advancing age bone marrow is progressively replaced with adipose tissue, accompanied by a concomitant decline in bone mass and strength. The mechanism underlying the increase in marrow fat and bone destruction remains elusive. We found that on the way of adipogenic differentiation of marrow str...

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Hlavní autoři: Takeshita, Sunao, Fumoto, Toshio, Naoe, Yoshinori, Ikeda, Kyoji
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059115/
https://ncbi.nlm.nih.gov/pubmed/24753250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.547919
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