Osteoclast-secreted CTHRC1 in the coupling of bone resorption to formation

Bone remodeling is characterized by the sequential, local tethering of osteoclasts and osteoblasts and is key to the maintenance of bone integrity. While bone matrix–mobilized growth factors, such as TGF-β, are proposed to regulate remodeling, no in vivo evidence exists that an osteoclast-produced m...

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Autori principali: Takeshita, Sunao, Fumoto, Toshio, Matsuoka, Kazuhiko, Park, Kyoung-ae, Aburatani, Hiroyuki, Kato, Shigeaki, Ito, Masako, Ikeda, Kyoji
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754269/
https://ncbi.nlm.nih.gov/pubmed/23908115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69493
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