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Osteoclast-secreted CTHRC1 in the coupling of bone resorption to formation

Bone remodeling is characterized by the sequential, local tethering of osteoclasts and osteoblasts and is key to the maintenance of bone integrity. While bone matrix–mobilized growth factors, such as TGF-β, are proposed to regulate remodeling, no in vivo evidence exists that an osteoclast-produced m...

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Bibliografiska uppgifter
Huvudupphovsmän: Takeshita, Sunao, Fumoto, Toshio, Matsuoka, Kazuhiko, Park, Kyoung-ae, Aburatani, Hiroyuki, Kato, Shigeaki, Ito, Masako, Ikeda, Kyoji
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754269/
https://ncbi.nlm.nih.gov/pubmed/23908115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69493
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