Osteoclast-secreted CTHRC1 in the coupling of bone resorption to formation

Bone remodeling is characterized by the sequential, local tethering of osteoclasts and osteoblasts and is key to the maintenance of bone integrity. While bone matrix–mobilized growth factors, such as TGF-β, are proposed to regulate remodeling, no in vivo evidence exists that an osteoclast-produced m...

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Autors principals: Takeshita, Sunao, Fumoto, Toshio, Matsuoka, Kazuhiko, Park, Kyoung-ae, Aburatani, Hiroyuki, Kato, Shigeaki, Ito, Masako, Ikeda, Kyoji
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754269/
https://ncbi.nlm.nih.gov/pubmed/23908115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69493
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