Genome-wide Association Study of Atazanavir Pharmacokinetics and Hyperbilirubinemia in AIDS Clinical Trials Group Protocol A5202

BACKGROUND: Atazanavir-associated hyperbilirubinemia can cause premature discontinuation of atazanavir and avoidance of its initial prescribing. We used genome-wide genotyping and clinical data to characterize determinants of atazanavir pharmacokinetics and hyperbilirubinemia in AIDS Clinical Trials...

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Detalhes bibliográficos
Main Authors: Johnson, Daniel H., Venuto, Charles, Ritchie, Marylyn D., Morse, Gene D., Daar, Eric S., McLaren, Paul J., Haas, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059003/
https://ncbi.nlm.nih.gov/pubmed/24557078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000034
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