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Probabilistic method for detecting copy number variation in a fetal genome using maternal plasma sequencing
Motivation: The past several years have seen the development of methodologies to identify genomic variation within a fetus through the non-invasive sequencing of maternal blood plasma. These methods are based on the observation that maternal plasma contains a fraction of DNA (typically 5–15%) origin...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4058944/ https://ncbi.nlm.nih.gov/pubmed/24931986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu292 |
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