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Detecting independent and recurrent copy number aberrations using interval graphs

Motivation: Somatic copy number aberrations (SCNAs) are frequent in cancer genomes, but many of these are random, passenger events. A common strategy to distinguish functional aberrations from passengers is to identify those aberrations that are recurrent across multiple samples. However, the extens...

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Detalhes bibliográficos
Main Authors: Wu, Hsin-Ta, Hajirasouliha, Iman, Raphael, Benjamin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058951/
https://ncbi.nlm.nih.gov/pubmed/24931984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu276
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