TLR9 Ligand (CpG Oligodeoxynucleotide) Induces CLL B-Cells to Differentiate into CD20(+) Antibody-Secreting Cells

B-cell chronic lymphocytic leukemia (CLL) is the most frequent adult leukemia in the Western world. It is a heterogeneous disease characterized by clonal proliferation and the accumulation of CD5(+) mature B lymphocytes. However, the normal counterpart from which the latter cells arise has not yet b...

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Autors principals: Ghamlouch, Hussein, Ouled-Haddou, Hakim, Guyart, Aude, Regnier, Aline, Trudel, Stéphanie, Claisse, Jean-François, Fuentes, Vincent, Royer, Bruno, Marolleau, Jean-Pierre, Gubler, Brigitte
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058906/
https://ncbi.nlm.nih.gov/pubmed/24982661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00292
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