Phorbol myristate acetate, but not CD40L, induces the differentiation of CLL B cells into Ab-secreting cells

In this study, we investigated the capacity of chronic lymphocytic leukemia (CLL) B cells to undergo terminal differentiation into Ig-secreting plasma cells in T cell-independent and T cell-dependent responses. We used a two-step model involving stimulation with phorbol myristate acetate (PMA) and C...

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Detalhes bibliográficos
Main Authors: Ghamlouch, Hussein, Ouled-Haddou, Hakim, Guyart, Aude, Regnier, Aline, Trudel, Stéphanie, Claisse, Jean-François, Fuentes, Vincent, Royer, Bruno, Marolleau, Jean-Pierre, Gubler, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134517/
https://ncbi.nlm.nih.gov/pubmed/24797583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2014.37
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