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Targeted Cytosolic Delivery of Cell-Impermeable Compounds by Nanoparticle-Mediated, Light-Triggered Endosome Disruption

Nanoparticle (NP)-mediated drug delivery typically relies on cargo release to occur passively or in response to environmental stimuli. Here we present a delivery method based on light-activated disruption of intracellular vesicles after internalization of biofunctionalized mesoporous silica nanopart...

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Detalhes bibliográficos
Main Authors: Febvay, Sébastien, Marini, Davide M., Belcher, Angela M., Clapham, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058846/
https://ncbi.nlm.nih.gov/pubmed/20446663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl101157z
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