Promoter Region Hypermethylation and mRNA Expression of MGMT and p16 Genes in Tissue and Blood Samples of Human Premalignant Oral Lesions and Oral Squamous Cell Carcinoma

Promoter methylation and relative gene expression of O(6)-methyguanine-DNA-methyltransferase (MGMT) and p16 genes were examined in tissue and blood samples of patients with premalignant oral lesions (PMOLs) and oral squamous cell carcinoma (OSCC). Methylation-specific PCR and reverse transcriptase P...

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Bibliographic Details
Main Authors: Bhatia, Vikram, Goel, Madhu Mati, Makker, Annu, Tewari, Shikha, Yadu, Alka, Shilpi, Priyanka, Kumar, Sandeep, Agarwal, S. P., Goel, Sudhir K.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058681/
https://ncbi.nlm.nih.gov/pubmed/24991542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/248419
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