Promoter Region Hypermethylation and mRNA Expression of MGMT and p16 Genes in Tissue and Blood Samples of Human Premalignant Oral Lesions and Oral Squamous Cell Carcinoma

Promoter methylation and relative gene expression of O(6)-methyguanine-DNA-methyltransferase (MGMT) and p16 genes were examined in tissue and blood samples of patients with premalignant oral lesions (PMOLs) and oral squamous cell carcinoma (OSCC). Methylation-specific PCR and reverse transcriptase P...

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Détails bibliographiques
Auteurs principaux: Bhatia, Vikram, Goel, Madhu Mati, Makker, Annu, Tewari, Shikha, Yadu, Alka, Shilpi, Priyanka, Kumar, Sandeep, Agarwal, S. P., Goel, Sudhir K.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058681/
https://ncbi.nlm.nih.gov/pubmed/24991542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/248419
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