Promoter Region Hypermethylation and mRNA Expression of MGMT and p16 Genes in Tissue and Blood Samples of Human Premalignant Oral Lesions and Oral Squamous Cell Carcinoma

Promoter methylation and relative gene expression of O(6)-methyguanine-DNA-methyltransferase (MGMT) and p16 genes were examined in tissue and blood samples of patients with premalignant oral lesions (PMOLs) and oral squamous cell carcinoma (OSCC). Methylation-specific PCR and reverse transcriptase P...

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Main Authors: Bhatia, Vikram, Goel, Madhu Mati, Makker, Annu, Tewari, Shikha, Yadu, Alka, Shilpi, Priyanka, Kumar, Sandeep, Agarwal, S. P., Goel, Sudhir K.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058681/
https://ncbi.nlm.nih.gov/pubmed/24991542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/248419
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