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Cenp-meta is required for sustained spindle checkpoint

Cenp-E is a kinesin-like motor protein required for efficient end-on attachment of kinetochores to the spindle microtubules. Cenp-E immunodepletion in Xenopus mitotic extracts results in the loss of mitotic arrest and massive chromosome missegregation, whereas its depletion in mammalian cells leads...

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Autori principali: Rubin, Thomas, Karess, Roger E., Rahmani, Zohra
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058087/
https://ncbi.nlm.nih.gov/pubmed/24876387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20148490
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