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Cenp-meta is required for sustained spindle checkpoint
Cenp-E is a kinesin-like motor protein required for efficient end-on attachment of kinetochores to the spindle microtubules. Cenp-E immunodepletion in Xenopus mitotic extracts results in the loss of mitotic arrest and massive chromosome missegregation, whereas its depletion in mammalian cells leads...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Company of Biologists
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4058087/ https://ncbi.nlm.nih.gov/pubmed/24876387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20148490 |
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