Indoleamine 2,3-dioxygenase mediates immune-independent human tumor cell resistance to olaparib, gamma radiation, and cisplatin

Indoleamine 2,3-dioxygenase-1 (IDO) is an immunosuppressive molecule expressed by most human tumors. IDO levels correlate with poor prognosis in cancer patients and IDO inhibitors are under investigation to enhance endogenous anticancer immunosurveillance. Little is known of immune-independent funct...

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Detalhes bibliográficos
Main Authors: Vareki, Saman Maleki, Rytelewski, Mateusz, Figueredo, Rene, Chen, Di, Ferguson, Peter J., Vincent, Mark, Min, Weiping, Zheng, Xiufen, Koropatnick, James
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058044/
https://ncbi.nlm.nih.gov/pubmed/24784564
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