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STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth

The dismal 5-year survival (<5%) for pancreatic cancer (PanCA) underscores the need for developing effective therapeutic options. Recent studies from our laboratory have shown that Nexrutine(®) (Nx), a bark extract from Phellodendron amurense exhibits excellent anticancer activity in human pancre...

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Bibliografiske detaljer
Main Authors: Gong, Jingjing, Muñoz, Amanda R., Chan, Daniel, Ghosh, Rita, Kumar, Addanki P.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058024/
https://ncbi.nlm.nih.gov/pubmed/24796733
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