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A framework for application of metabolic modeling in yeast to predict the effects of nsSNV in human orthologs
BACKGROUND: We have previously suggested a method for proteome wide analysis of variation at functional residues wherein we identified the set of all human genes with nonsynonymous single nucleotide variation (nsSNV) in the active site residue of the corresponding proteins. 34 of these proteins were...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4057618/ https://ncbi.nlm.nih.gov/pubmed/24894379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-9-9 |
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