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A framework for application of metabolic modeling in yeast to predict the effects of nsSNV in human orthologs
BACKGROUND: We have previously suggested a method for proteome wide analysis of variation at functional residues wherein we identified the set of all human genes with nonsynonymous single nucleotide variation (nsSNV) in the active site residue of the corresponding proteins. 34 of these proteins were...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4057618/ https://ncbi.nlm.nih.gov/pubmed/24894379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-9-9 |
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