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Anti-cancer activity of glucosamine through inhibition of N-linked glycosylation

BACKGROUND: We have reported that the glucosamine suppressed the proliferation of the human prostate carcinoma cell line DU145 through inhibition of STAT3 signaling. DU145 cells autonomously express IL-6 and the IL-6/STAT3 signaling is activated. IL-6 receptor subunits are subject to N-glycosylation...

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Autori principali: Chesnokov, Viktor, Gong, Beata, Sun, Chao, Itakura, Keiichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057579/
https://ncbi.nlm.nih.gov/pubmed/24932134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-14-45
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