Glucosamine Modulates T Cell Differentiation through Down-regulating N-Linked Glycosylation of CD25

Glucosamine has immunomodulatory effects on autoimmune diseases. However, the mechanism(s) through which glucosamine modulates different T cell subsets and diseases remain unclear. We demonstrate that glucosamine impedes Th1, Th2, and iTreg but promotes Th17 differentiation through down-regulating N...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Chien, Ming-Wei, Lin, Ming-Hong, Huang, Shing-Hwa, Fu, Shin-Huei, Hsu, Chao-Yuan, Yen, B. Lin-Ju, Chen, Jiann-Torng, Chang, Deh-Ming, Sytwu, Huey-Kang
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705938/
https://ncbi.nlm.nih.gov/pubmed/26468284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.674671
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