Peptide conjugation to an in vitro-selected DNA ligand improves enzyme inhibition.

An in vitro selection technique was used to identify a specific high-affinity DNA ligand targeted to human neutrophil elastase (HNE). 1H NMR data and a comparative analysis of the selected sequences suggest that the DNA folds into a G-quartet structure with duplexed ends. The high-affinity binding D...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lin, Y, Padmapriya, A, Morden, K M, Jayasena, S D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC40567/
https://ncbi.nlm.nih.gov/pubmed/7479933
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi