A truncating SCN5A mutation combined with genetic variability causes sick sinus syndrome and early atrial fibrillation

BACKGROUND: Mutations in the SCN5A gene, encoding the α-subunit of the cardiac Na(+) channel, Na(v)1.5, can result in several life-threatening arrhythmias. OBJECTIVE: To characterize a distal truncating SCN5A mutation, R1860Gfs*12, identified in a family with different phenotypes including sick sinu...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Ziyadeh-Isleem, Azza, Clatot, Jérôme, Duchatelet, Sabine, Gandjbakhch, Estelle, Denjoy, Isabelle, Hidden-Lucet, Françoise, Hatem, Stéphane, Deschênes, Isabelle, Coulombe, Alain, Neyroud, Nathalie, Guicheney, Pascale
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056672/
https://ncbi.nlm.nih.gov/pubmed/24582607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2014.02.021
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller