Targeting the programmed cell death 1: programmed cell death ligand 1 pathway reverses T cell exhaustion in patients with sepsis

INTRODUCTION: A major pathophysiologic mechanism in sepsis is impaired host immunity which results in failure to eradicate invading pathogens and increased susceptibility to secondary infections. Although many immunosuppressive mechanisms exist, increased expression of the inhibitory receptor progra...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chang, Katherine, Svabek, Catherine, Vazquez-Guillamet, Cristina, Sato, Bryan, Rasche, David, Wilson, Strother, Robbins, Paul, Ulbrandt, Nancy, Suzich, JoAnn, Green, Jonathan, Patera, Andriani C, Blair, Wade, Krishnan, Subramaniam, Hotchkiss, Richard
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2014
Θέματα:
Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056005/
https://ncbi.nlm.nih.gov/pubmed/24387680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13176
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