Targeting the programmed cell death 1: programmed cell death ligand 1 pathway reverses T cell exhaustion in patients with sepsis

INTRODUCTION: A major pathophysiologic mechanism in sepsis is impaired host immunity which results in failure to eradicate invading pathogens and increased susceptibility to secondary infections. Although many immunosuppressive mechanisms exist, increased expression of the inhibitory receptor progra...

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Detaylı Bibliyografya
Asıl Yazarlar: Chang, Katherine, Svabek, Catherine, Vazquez-Guillamet, Cristina, Sato, Bryan, Rasche, David, Wilson, Strother, Robbins, Paul, Ulbrandt, Nancy, Suzich, JoAnn, Green, Jonathan, Patera, Andriani C, Blair, Wade, Krishnan, Subramaniam, Hotchkiss, Richard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056005/
https://ncbi.nlm.nih.gov/pubmed/24387680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13176
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