Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15

Adoptive transfer of T lymphocytes expressing a CD19-specific chimeric antigen receptor (CAR.CD19) induces complete tumor regression in patients with lymphoid malignancies. Although in vivo persistence of CAR-T cells correlates with clinical responses, it remains unknown whether specific cell subset...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Xu, Yang, Zhang, Ming, Ramos, Carlos A., Durett, April, Liu, Enli, Dakhova, Olga, Liu, Hao, Creighton, Chad J., Gee, Adrian P., Heslop, Helen E., Rooney, Cliona M., Savoldo, Barbara, Dotti, Gianpietro
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2014
Assuntos:
Gene Therapy
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055922/
https://ncbi.nlm.nih.gov/pubmed/24782509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-552174
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares