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IκB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-κB in the central nervous system

The IκB kinase complex induces nuclear factor kappa B activation and has recently been recognized as a key player of autoimmunity in the central nervous system. Notably, IκB kinase/nuclear factor kappa B signalling regulates peripheral myelin formation by Schwann cells, however, its role in myelin f...

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Autors principals: Raasch, Jenni, Zeller, Nicolas, van Loo, Geert, Merkler, Doron, Mildner, Alexander, Erny, Daniel, Knobeloch, Klaus-Peter, Bethea, John R., Waisman, Ari, Knust, Markus, Del Turco, Domenico, Deller, Thomas, Blank, Thomas, Priller, Josef, Brück, Wolfgang, Pasparakis, Manolis, Prinz, Marco
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055835/
https://ncbi.nlm.nih.gov/pubmed/21310728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awq359
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