New Environment-Sensitive Multichannel DNA Fluorescent Label for Investigation of the Protein-DNA Interactions

Here, we report the study of a new multichannel DNA fluorescent base analogue 3-hydroxychromone (3HC) to evaluate its suitability as a fluorescent reporter probe of structural transitions during protein-DNA interactions and its comparison with the current commercially available 2-aminopurine (aPu),...

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Bibliographic Details
Main Authors: Kuznetsova, Alexandra A., Kuznetsov, Nikita A., Vorobjev, Yuri N., Barthes, Nicolas P. F., Michel, Benoît Y., Burger, Alain, Fedorova, Olga S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055743/
https://ncbi.nlm.nih.gov/pubmed/24925085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100007
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