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Sialidase NEU3 Dynamically Associates to Different Membrane Domains Specifically Modifying Their Ganglioside Pattern and Triggering Akt Phosphorylation

Lipid rafts are known to regulate several membrane functions such as signaling, trafficking and cellular adhesion. The local enrichment in sphingolipids and cholesterol together with the low protein content allows their separation by density gradient flotation after extraction with non-ionic deterge...

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Detalhes bibliográficos
Main Authors: Bonardi, Dario, Papini, Nadia, Pasini, Mario, Dileo, Loredana, Orizio, Flavia, Monti, Eugenio, Caimi, Luigi, Venerando, Bruno, Bresciani, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055604/
https://ncbi.nlm.nih.gov/pubmed/24925219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099405
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