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Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops

BACKGROUND: Large surface loops contained within compact protein structures and not involved in catalytic process have been proposed as preferred regions for protein family evolution. These loops are subjected to lower sequence constraints and can evolve rapidly in novel structural variants. A good...

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Detalhes bibliográficos
Main Authors: Giacopuzzi, Edoardo, Barlati, Sergio, Preti, Augusto, Venerando, Bruno, Monti, Eugenio, Borsani, Giuseppe, Bresciani, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179935/
https://ncbi.nlm.nih.gov/pubmed/21861893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-12-45
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