Computational Design of Apolipoprotein E4 Inhibitors for Alzheimer's Disease Therapy from Traditional Chinese Medicine

Apolipoprotein E4 (Apo E4) is the major genetic risk factor in the causation of Alzheimer's disease (AD). In this study we utilize virtual screening of the world's largest traditional Chinese medicine (TCM) database and investigate potential compounds for the inhibition of ApoE4. We presen...

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Hlavní autoři: Huang, Hung-Jin, Chen, Hsin-Yi, Lee, Cheng-Chun, Chen, Calvin Yu-Chian
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055423/
https://ncbi.nlm.nih.gov/pubmed/24967370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/452625
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