Computational Design of Apolipoprotein E4 Inhibitors for Alzheimer's Disease Therapy from Traditional Chinese Medicine

Apolipoprotein E4 (Apo E4) is the major genetic risk factor in the causation of Alzheimer's disease (AD). In this study we utilize virtual screening of the world's largest traditional Chinese medicine (TCM) database and investigate potential compounds for the inhibition of ApoE4. We presen...

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Bibliografiske detaljer
Main Authors: Huang, Hung-Jin, Chen, Hsin-Yi, Lee, Cheng-Chun, Chen, Calvin Yu-Chian
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055423/
https://ncbi.nlm.nih.gov/pubmed/24967370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/452625
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