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Design and synthesis of molecular probes for the determination of the target of the anthelmintic drug praziquantel
Schistosomiasis is a highly prevalent neglected tropical disease caused by blood-dwelling helminths of the genus Schistosoma. Praziquantel (PZQ) is the only drug available widely for the treatment of this disease and is administered in racemic form, even though only the (R)-isomer has significant an...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4055354/ https://ncbi.nlm.nih.gov/pubmed/24775301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.04.014 |
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