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Inhibition or Knockdown of ABC Transporters Enhances Susceptibility of Adult and Juvenile Schistosomes to Praziquantel

Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease that affects hundreds of millions. Treatment of schistosomiasis depends almost entirely on the drug praziquantel (PZQ). Though essential to treating and controlling schistosomiasis, a major limitation of...

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Detalhes bibliográficos
Main Authors: Kasinathan, Ravi S., Sharma, Lalit Kumar, Cunningham, Charles, Webb, Thomas R., Greenberg, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199547/
https://ncbi.nlm.nih.gov/pubmed/25330312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003265
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