Extracellular chloride regulation of Kv2.1, contributor to the major outward Kv current in mammalian outer hair cells

Outer hair cells (OHC) function as both receptors and effectors in providing a boost to auditory reception. Amplification is driven by the motor protein prestin, which is under anionic control. Interestingly, we now find that the major, 4-AP-sensitive, outward K(+) current of the OHC (I(K)) is also...

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Bibliografiske detaljer
Main Authors: Li, Xiantao, Surguchev, Alexei, Bian, Shumin, Navaratnam, Dhasakumar, Santos-Sacchi, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Membrane Transporters, Ion Channels and Pumps
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054960/
https://ncbi.nlm.nih.gov/pubmed/21940671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00177.2011
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