Ładuje się......
Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
Exchange of extracellular cystine for intracellular glutamate by the antiporter system x(c)(−) is implicated in numerous pathologies. Pharmacological agents that inhibit system x(c)(−) activity with high potency have long been sought, but have remained elusive. In this study, we report that the smal...
Zapisane w:
| Główni autorzy: | , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
eLife Sciences Publications, Ltd
2014
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054777/ https://ncbi.nlm.nih.gov/pubmed/24844246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02523 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|