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The GAFa domain of phosphodiesterase-6 contains a rod outer segment localization signal

Phosphodiesterase – 6 (PDE6) is a peripheral membrane protein synthesized in the inner segment of photoreceptor cells. Newly synthesized PDE6 is transported to the outer segment (OS) where it serves as a key effector enzyme in the phototransduction cascade. Proper localization of PDE6 in photorecept...

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Main Authors: Cheguru, Pallavi, Zhang, Zhongming, Artemyev, Nikolai O.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054601/
https://ncbi.nlm.nih.gov/pubmed/24147783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12501
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