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RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments

Prenylation is the posttranslational modification of a carboxyl-terminal cysteine residue of proteins that terminate with a CAAX motif. Following prenylation, the last three amino acids are cleaved off by the endoprotease, RAS-converting enzyme 1 (RCE1), and the prenylcysteine residue is methylated....

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Autors principals: Christiansen, Jeffrey R., Kolandaivelu, Saravanan, Bergo, Martin O., Ramamurthy, Visvanathan
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102416/
https://ncbi.nlm.nih.gov/pubmed/21555557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103627108
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