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Phosphorylation of Highly Conserved Serine Residues in the Influenza A Virus Nuclear Export Protein NEP Plays a Minor Role in Viral Growth in Human Cells and Mice

Phosphorylation at the highly conserved serine residues S23 to S25 in the nuclear export protein (NEP) of influenza A viruses was suspected to regulate its nuclear export activity or polymerase activity-enhancing function. Mutation of these phosphoacceptor sites to either alanine or aspartic acid sh...

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Detalhes bibliográficos
Main Authors: Reuther, Peter, Giese, Sebastian, Götz, Veronika, Riegger, David, Schwemmle, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054461/
https://ncbi.nlm.nih.gov/pubmed/24741082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00854-14
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