Roscovitine Inhibits EBNA1 Serine 393 Phosphorylation, Nuclear Localization, Transcription, and Episome Maintenance

Latent Epstein-Barr virus (EBV) infection causes human lymphomas and carcinomas. EBV usually persists as an episome in malignant cells. EBV episome persistence, replication, and gene expression are dependent on EBNA1 binding to multiple cognate sites in oriP. To search for inhibitors of EBNA1- and o...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kang, Myung-Soo, Lee, Eun Kyung, Soni, Vishal, Lewis, Timothy A., Koehler, Angela N., Srinivasan, Viswanathan, Kieff, Elliott
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2011
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067954/
https://ncbi.nlm.nih.gov/pubmed/21209116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01628-10
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares