Vaginal Myeloid Dendritic Cells Transmit Founder HIV-1

We report that primary human vaginal dendritic cells (DCs) display a myeloid phenotype and express CD4, CCR5, and CXCR4. Vaginal CD13(+) CD11c(+) DCs rapidly and efficiently bound transmitted/founder (T/F) CCR5-tropic (R5) viruses, transported them through explanted vaginal mucosa, and transmitted t...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Shen, Ruizhong, Kappes, John C., Smythies, Lesley E., Richter, Holly E., Novak, Lea, Smith, Phillip D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054437/
https://ncbi.nlm.nih.gov/pubmed/24741097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00766-14
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk